Vitamin B1
How Vitamin B1 Works
Work
・ Convert sugar into energy
・ Involved in alcohol metabolism
・ Involved in the work of the brain
・ Keep nerves working normally
Symptoms that are likely to occur when insufficient
Stiff shoulders, muscle aches, fatigue, alcoholism,
Beriberi, loss of appetite, poor memory, poor concentration,
Sound hypersensitivity, neuritis, Wernicke’s encephalopathy *
- Wernicke’s encephalopathy caused by a deficiency of vitamin B1 (thiamine) and Korsakoff’s syndrome, which is a sequela.
Wernicke-Korsakov syndrome, which is caused by a deficiency of vitamin B1 (thiamine) and is a sequela of Wernicke encephalopathy, is called Wernicke-Korsakov syndrome.A deficiency of thiamine causes Wernicke’s encephalopathy, which is characterized by varying degrees of impaired consciousness, ocular motility, and cerebellar ataxia, from mild to coma. Ocular motility disorders typically do not move the eye at all, but also include fine eye tremors (nystagmus). Cerebellum ataxia is a symptom in which the cerebellum becomes ill and the body sways and falls when standing or sitting, or the limbs cannot move as expected. A large amount of thiamine can save lives, but if left untreated, it will die.
Causes of thiamine deficiency include alcoholism (large amounts of alcohol impair the absorption of thiamine, and many addicted people drink only and do not eat), eating disorders, and pregnancy. For example, bad luck.However, even if life is saved, about 80% of the patients will have a sequelae called amnesia syndrome (Korsakoff syndrome), which is characterized by amnesia. This is a disease that literally focuses on amnesia, and although the ability to understand and calculate is relatively maintained, the memory is significantly reduced. You may lose your memory before you get sick (retrograde amnesia) or you may not be able to remember new things (anterograde amnesia). In severe cases, cognitive functions other than memory may be impaired and dementia may be diagnosed.
References
https://www.e-healthnet.mhlw.go.jp/information/dictionary/alcohol/ya-052.html
Foods high in vitamin B1
The amount of vitamin B1 required per meal is 0.32 mg.
The following vegetables are high in vitamin B1.
Asparagus
broccoli
Shiso
Basil etc.
About B vitamins
B vitamins are essential nutrients for creating energy for us to live.
It is difficult to exert the effect with only one of the B vitamins,
We work while helping each other.
Therefore, it is desirable to take the B vitamins together (complex).
B vitamins are widespread in animal and vegetable foods
B vitamins are common in the Japanese diet
It’s easy to think that there will be no shortage,
In reality, there are likely to be a significant number of potential deficiencies.
Types of B vitamins
As a nutrient belonging to the B vitamin group,
Vitamin B1, Vitamin B2, Vitamin B6, Niacin, Pantothenic Acid,
There are biotin, vitamin B12, folic acid, etc.
An environment where the B vitamins taken from food can work
The B vitamins taken from food cannot work immediately.
Once changed to a form that can work in the body (active type),
I will finally be able to work.
At this time, various B vitamins are related to each other in order to be able to work.
For example, niacin and vitamin B12 can be added to folic acid.
Vitamin B2 is required for vitamin B6.
At the same time, some require nucleic acids.
Therefore, in the vitamin B group that I ate
To work efficiently in your body
The B vitamins are complex, not simple substances
Ideally, the nucleic acid component should be taken together.
Enzymes and Coenzymes
The inside of a person’s body is made up of various chemical reactions.
Reduce the energy at which the reaction takes place,
Enzymes make it possible to react smoothly.
In the process of evolution of living things
There was a limit to the reactions that could be catalyzed only by proteins.
So, an enzyme containing a non-proteinaceous cofactor
What you have acquired in the process of evolution has survived.
This non-proteinaceous thing is a coenzyme or cofactor,
Or it is called a prosthetic group, it is a mineral itself,
It may contain vitamins.
In addition, the active form in which the protein part is bound to apoenzyme and coenzyme
It is called holoenzyme.
When the enzyme that takes this form becomes a holo enzyme,
For the first time, you will be able to perform its function and work.
Energy metabolism is in the TCA cycle (a circuit in the process of producing energy)
It will be done smoothly by entering.
At this time, vitamin B group is required.
TCA cycle and amino acid metabolism
In the TCA cycle and amino acid metabolism,
Each B vitamin is involved as shown in the figure. (Simplified.)
Proteins, energy sources, oxygen, which are the materials of enzymes,
And only when you have enough B vitamins and vitamin C
You can create energy well.
B1 Vitamin B1 → TPP
B2 Vitamin B2 → FAD
N niacin → NAD +, NADPH
P pantothenic acid → CoASH
B6 Vitamin B6
B12 Vitamin B12
F folic acid → THF
Bio biotin
C Vitamin C
Reasons for lack of B vitamins
Vitamin B complex is said to be one of the nutrients that are easily deficient in modern times.
The possible reasons for this are as follows.
- Changes in foods The B vitamins are reduced by refining, processing, and preserving foods.
- Refined white foods with increased consumption of B vitamins,
Stress, excessive alcohol intake, pregnancy, breastfeeding, aging,
Vitamin B group consumption increases due to overeating, etc. - Long-term administration of antibiotics B vitamins are made by bacteria in the intestines,
For those who have been taking antibiotics for a long time,
Bacterial balance in the intestine is disturbed,
The amount of vitamin B6 etc. synthesized is reduced.
B vitamins and antioxidants
It is also reported that the B vitamins have a function of protecting lipids from rust (oxidation).
Vitamin B group deficiency check
Check the following items.
If so, you may be deficient in B vitamins.
·Get tired easily
・ I can’t get tired even if I sleep
・ Become sleepy during the day
・ I can’t keep my concentration
·get annoyed
・ Stiff shoulders do not heal easily
・ Easy to develop stomatitis and angular cheilitis
・ Easy to catch a cold
・ Numbness in the lower limbs